The fourth-gen Sienna, designed by the combined effort of CALTY’s Newport Beach, CA and Ann Arbor, MI studios, delivers a combination of room, comfort, convenience, fuel efficiency and versatility. The 2021 Sienna’s Toyota Hybrid System II delivers 245 total horsepower and an EPA-estimated 36 combined MPG fuel economy, the latter setting a benchmark for the segment, all while operating seamlessly and transparently.